Phalloidin-PAINT featured on the cover of Biophysical Journal.

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Hirushi's work leveraging transient binding of dye-conjugated phalloidin to achieve quantitative superresolution imaging of F-actin is published in Biophysical Journal. Through her work, she successfully captured intricate F-actin-associated membrane fibers of dendritic cells (DCs), which are often lost during the washing steps in standard staining procedures. She quantitatively characterized the spatial redistribution of F-actin in DCs following lipopolysaccharide stimulation. Her work opens new possibilities to quantitative "PAINT" proteins using small molecules. Congrats, Hirushi!