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* Corresponding author
 Equal contribution
# Undergraduate and K12 researcher


37. B Saed, NT Ramseier, T Perera, J Anderson#, J Burnett, H Gunasekara, A Burgess, H Jing, YS Hu*, Increased Vesicular Dynamics and Nanoscale Clustering of IL-2 after T Cell Activation. Biophys J. 2024. Published online. Link.

36. X Geng, C Wang, S Abdelrahman, T Perera, B Saed, YS Hu, A Wolfe, J Reneau, C Murga-Zamalloa, RA Wilcox*. GATA-3 Dependent Gene Transcription is Impaired upon HDAC Inhibition. Clin. Cancer Res. 2024;30(5):1054–1066. PMID: 38165708; PMCID: PMC10922852 Link.



35. T Perera, H Gunasekara, YS Hu*. Single-Molecule Localization Microscopy Using Time-Lapse Imaging of Single-Antibody Labeling. Curr. Protoc. 2023;3(10):e908. PMID: 37830764; PMCID: PMC10593501. pdf Link.

34. H Gunasekara, T Perera, J Anderson#, B Saed, N Ramseier, K Neama#, YS Hu*. Superresolution Imaging with Single-Antibody Labeling. Bioconjug. Chem. 2023;34(5):825-833. PMID: 37145839; PMCID: PMC10859171. pdf Link

33. HB Chandrasiri, H Jing, T Perera, YS Hu, PT Snee*. Fluorescence Intermittency of Quantum Dot-Organic Dye Conjugates: Implications for Alternative Energy and Biological Imaging. J Phys Chem Lett. 2023;14(15):3621-3626. PMID: 37023397. Link


32. X Geng, C Wang, X Gao, P Chowdhury, J Weiss, J Villegas, B Saed, T Perera, Y Hu, J Reneau, M Sverdlov, A Wolfe, N Brown, P Harms, N Bailey, K Inamdar, A Hristov, T Tejasvi, J Montes, C Barrionuevo, L Taxa, S Casavilca-Zambrano, L Lage, H Culler, J Pereira, J Runge, T Qin, L Tsoi, H Hong, L Zhang, C Lyssiotis, R Ohe, T Toubai, A Zevallos-Morales, C Murga-Zamalloa, and R Wilcox*, GATA-3 is a proto-oncogene in T-cell lymphoproliferative neoplasms, Blood Cancer J (Nature), 2022. PMID: 36329027 PMCID: PMC9633835 Link

31. H Jing, B Saed, M Pálmai, H Gunasekara, PT Snee, YS Hu*, Fluorescent artificial antigens revealed extended membrane networks utilized by live dendritic cells for antigen uptake, Nano Lett, 2022. PMID: 35499493 pdf Link

30. Y Jiang, S Krantz, X Qin, S Li, H Gunasekara, Y-M Kim, A Zimnicka, M Bae, K Ma, PT Toth,  Y Hu, AN Shajahan-Haq, HH Patel, S Gentile, MG Bonini, J Rehman, Y Liu, RD Minshall*, Caveolin-1 controls mitochondrial damage and ROS production by regulating fission-fusion dynamics and mitophagy, Redox Biol, 2022. PMID: 35413643 PMCID: PMC9018165 pdf Link

29. H Gunasekara, R Munaweera, YS Hu*, Chaotropic perturbation of noncovalent interactions of the hemagglutinin tag monoclonal antibody fragment enables superresolution molecular census, ACS Nano, 2022. PMID: 34797055 pdf Link Correction: H Gunasekara, R Munaweera, L Novotná, BF Lillemeier*, YS Hu*, ACS Nano, 2022. PMID: 36417787 pdf Link

ACS Nano


28. Z-J Jiang, W Li, L-H Yao, B Saed, Y Rao, BS Grewe, A McGinley, K Varga, S Alford, YS Hu, L-W Gong*, TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis, eLife, 2021. PMID: 34569930 PMCID: PMC8516418 Link

27. B Saed, R Munaweera, J Anderson#, W O’Neill*,  YS Hu*, Rapid statistical discrimination of fluorescence images of T cell receptors on immobilizing surfaces with different coating conditions, Sci Rep, 2021. PMID: 34326382 PMCID: PMC8322097 pdf Link

26. H Jing, M Pálmai, B Saed, A George, PT Snee, YS Hu*, Cytosolic delivery of membrane-penetrating QDs into T cell lymphocytes: implications in immunotherapy and drug delivery, Nanoscale, 2021. PMID: 33688882 pdf Link

25. R Munaweera and YS Hu*, Computational characterizations of the interactions between the pontacyl violet 6R and exoribonuclease as a potential drug target against SARS-CoV-2, Front Chem, 2021. PMID: 33553109 PMCID: PMC7858249 pdf Link


24. NA Szydlowski#, H Jing, M Alqashmi#, YS Hu*, Cell phone digital microscopy using an oil droplet, Biomed Opt Express, 11(5), 2328-2338, 2020. PMID: 32499926 PMCID: PMC7249838 pdf Link


23. NA Szydlowski#,⫽, JS Go#,⫽YS Hu*, Chromatin imaging and new technologies for imaging the nucleome, WIREs Systems Biology and Medicine, e1442, 2019. PMID: 30456928 pdf Link

Publications prior to UIC Heading link

22. BD Stein, D Calzolari, K Hellberg, YS Hu, L He, C-M Hung, EQ Toyama, DS Ross, BF Lillemeier, LC Cantley, JR Yates III, RJ Shaw, Quantitative in vivo proteomics of metformin response in liver reveals AMPK-dependent and independent signaling networks, Cell Rep, 29, 2019. pdf Link

21. H Ren, B Yang, C Ma, YS Hu, PG Wang, L Wang, Cysteine sulfoxidation increases the photostability of red fluorescent proteins, ACS Chem Biol, 11(10), 2016. pdf Link

20. YS Hu, H Cang, and B Lillemeier, Super-resolution imaging reveals nanometer- and micrometer-scale spatial distributions of T cell receptors in lymph nodes, PNAS, 113(26), 2016. pdf Link

19. AL Chen, MA Jackson, AY Lin, ER Figueroa, YS Hu, ER Evans, V Asthana, JK Young, RA Drezek, Changes in optical properties of plasmonic nanoparticles in cellular environments are modulated by nanoparticle PEGylation and serum conditions, Nanoscale Res Lett, 11(303), 2016. pdf Link

18. AL Chen, YS Hu, MA Jackson, AY Lin, JK Young, RJ Langsner, RA Drezek, Quantifying spectral changes experienced by plasmonic nanoparticles in a cellular environment to inform biomedical nanoparticle design, Nanoscale Res Lett, 9(1), 2014. pdf Link

17. XH Chen, Z Xiang, YS Hu, VK Lacey, H Cang, L Wang, Genetically encoding an electrophilic amino acid for protein stapling and covalent binding to native receptors, ACS Chem Biol, 9(9), 2014. pdf Link

16. YS Hu, M Zimmerley, Y Li, R Watters, H Cang, Single‐molecule super‐resolution light‐sheet microscopy, ChemPhysChem, 15(4), 2014. pdf Link

15. Y Li, Y Hu, H Cang, Light sheet microscopy for tracking single molecules on the apical surface of living cells, J Phys Chem B, 117(49), 2013. pdf Link

14. YS Hu, Q Zhu, K Elkins, K Tse, Y Li, J Fitzpatrick, IM Verma, H Cang, Light-sheet Bayesian microscopy enables deep-cell super-resolution imaging of heterochromatin in live human embryonic cells, Opt Nanoscopy, 2(7), 2013. pdf Link

13. Z Xiang, H Ren, YS Hu, I Coin, J Wei, H Cang, L Wang, Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity, Nat Methods, 10(9), 2013. pdf Link

12. YS Hu, X Nan, P Sengupta, J Lippincott-Schwartz, H Cang, Accelerating 3B single-molecule super-resolution microscopy with cloud computing, Nat Methods, 10(2), 2013. pdf Link

11. AT Zayak, H Choo, YS Hu, DJ Gargas, S Cabrini, J Bokor, PJ Schuck, JB Neaton, Harnessing chemical Raman enhancement for understanding organic adsorbate binding on metal surfaces, J Phys Chem Lett, 3(10), 2012. pdf Link

10. AT Zayak, YS Hu, H Choo, J Bokor, S Cabrini, PJ Schuck, JB Neaton, Chemical Raman enhancement of organic adsorbates on metal surfaces, Phys Rev Lett, 106(8), 2011. pdf Link

9. LC Kennedy, LR Bickford, NA Lewinski, AJ Coughlin, Y Hu, ES Day, JL West, RA Drezek, A new era for cancer treatment: gold‐nanoparticle‐mediated thermal therapies,  Small, 7(2), 2011. pdf Link

8. YS Hu, J Jeon, TJ Seok, S Lee, JH Hafner, RA Drezek, H Choo, Enhanced Raman scattering from nanoparticle-decorated nanocone substrates: a practical approach to harness in-plane excitations, ACS Nano, 4(10), 2010. pdf Link

7. E Lukianova-Hleb, Y Hu, L Latterini, L Tarpani, S Lee, RA Drezek, JH Hafner, DO Lapotko, Plasmonic nanobubbles as transient vapor nanobubbles generated around plasmonic nanoparticles,  ACS Nano, 4(4), 2010. pdf Link

6. YS Hu, SJ Noelck, RA Drezek, Symmetry breaking in gold-silica-gold multilayer nanoshells, ACS Nano, 4(3), 2010. pdf Link

5. Y Hu, RC Fleming, RA Drezek, Optical properties of gold-silica-gold multilayer nanoshells, Opt Express, 16(24). 2008. pdf Link

4. Y Hu, DR Jackson, JT Williams, SA Long, VR Komanduri, Characterization of the input impedance of the inset-fed rectangular microstrip antenna, IEEE Trans Antennas Propag, 56(10), 2008. pdf Link

3. Y Hu, TA Nieminen, NR Heckenberg, H Rubinsztein-Dunlop, Antireflection coating for improved optical trapping, J Appl Phys, 103(9), 2008. pdf Link

2. EY Hleb, Y Hu, RA Drezek, JH Hafner, DO Lapotko, Photothermal bubbles as optical scattering probes for imaging living cells, Future Medicine Ltd, 3(6), 2008. Link

1. LR Bickford, J Chang, K Fu, J Sun, Y Hu, A Gobin, TK Yu, RA Drezek, Evaluation of immunotargeted gold nanoshells as rapid diagnostic imaging agents for HER2-overexpressing breast cancer cells: a time-based analysis, Nanotechnology, 4(1), 2008. pdf Link

Full list of publications